Journal article
Behavioral sensitization to cocaine is not associated with changes in serotonin (5-HT) fiber immunoreactivity in rat forebrain
Abstract
We investigated whether cocaine-induced behavioral sensitization is associated with changes in serotonin (5-HT) immunoreactivity. Male Sprague-Dawley rats were injected with either cocaine (15 mg/kg, IP) or saline twice daily for seven days. Their behavior was observed and rated for locomotor activation and stereotypy. One day after the final injection, the brains were processed for 5-HT immunohistochemistry. The intensity of 5-HT …
Authors
Paris JM; Callahan PM; Lee JM; Cunningham KA
Journal
Brain Research Bulletin, Vol. 27, No. 6, pp. 843–847
Publisher
Elsevier
Publication Date
12 1991
DOI
10.1016/0361-9230(91)90220-e
ISSN
0361-9230