History, challenges and perspectives of cell microencapsulation Journal Articles uri icon

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  • Cell microencapsulation continues to hold significant promise for biotechnology and medicine. The controlled, and continuous, delivery of therapeutic products to the host by immunoisolated cells is a potentially cost-effective method to treat a wide range of diseases. Although there are several issues that need to be addressed, including capsule manufacture, properties and performance, in the past few years, a stepwise analysis on the essential obstacles and limitations has brought the whole technology closer to a realistic proposal for clinical application. This paper summarizes the current situation in the cell encapsulation field and discusses the main events that have occurred along the way.


  • Orive, Gorka
  • Maria Hernández, Rose
  • Rodrı́guez Gascón, Alicia
  • Calafiore, Riccardo
  • Swi Chang, Thomas Ming
  • Vos, Paul de
  • Hortelano, Gonzalo
  • Hunkeler, David
  • Lacı́k, Igor
  • Luis Pedraz, José

publication date

  • February 2004