Gabapentin does not improve multimodal analgesia outcomes for total knee arthroplasty: a randomized controlled trial

PurposeThis study assessed whether gabapentin given preoperatively and for two days postoperatively (in addition to patient-controlled analgesia [PCA] morphine, acetaminophen, and ketorolac) is effective in reducing morphine requirements and moderating pain scores when compared with placebo for primary total knee arthroplasty.MethodsThis single-centre double-blind randomized controlled trial was undertaken in patients who underwent primary …