Mental and motor development before and during growth hormone treatment in infants and toddlers with Prader–Willi syndrome

Abstract

BACKGROUND: Prader-Willi syndrome (PWS) is a neurogenetic disorder characterized by muscular hypotonia, psychomotor delay, feeding difficulties and failure to thrive in infancy. GH treatment improves growth velocity and body composition. Research on the effects of GH on psychomotor development in infants with PWS is limited. OBJECTIVE: To evaluate psychomotor development in PWS infants and toddlers during GH treatment compared to randomized …

Authors

Festen DAM; Wevers M; Lindgren AC; Böhm B; Otten BJ; Wit JM; Duivenvoorden HJ; Hokken‐Koelega ACS

Journal

Clinical Endocrinology, Vol. 68, No. 6, pp. 919–925

Publisher

Wiley

Publication Date

6 2008

DOI

10.1111/j.1365-2265.2007.03126.x

ISSN

0300-0664

Associated Experts

Helga Duivenvoorden

Assistant Professor (Part-Time), Faculty of Health Sciences

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