Prevalence and correlates of airflow obstruction in  317 000 never-smokers in China Academic Article uri icon

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abstract

  • In China, the burden of chronic obstructive disease (COPD) is high in never-smokers but little is known about its causes in this group. We analysed data on 287 000 female and 30 000 male never-smokers aged 30-79 years from 10 regions in China, who participated in the China Kadoorie Biobank baseline survey (2004-2008). Prevalence of airflow obstruction (AFO) (pre-bronchodilator forced expiratory volume in 1 s (FEV1)/forced vital capacity (FVC) <0.7 and below the lower limit of normal (LLN)) was estimated, by age and region. Cross-sectional associations of AFO (FEV1/FVC <0.7), adjusted for confounding, were examined. AFO prevalence defined as FEV1/FVC <0.7 was 4.0% in females and 5.1% in males (mean ages 51 and 54 years, respectively). AFO prevalence defined as FEV1/FVC

authors

  • Smith, M
  • Li, L
  • Augustyn, M
  • Kurmi, Om
  • Chen, J
  • Collins, R
  • Guo, Y
  • Han, Y
  • Qin, J
  • Xu, G
  • Wang, J
  • Bian, Z
  • Zhou, G
  • Peto, R
  • Chen, Z

publication date

  • July 1, 2014

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