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The Role of the Randomized Controlled Trial in...
Journal article

The Role of the Randomized Controlled Trial in Plastic Surgery

Abstract

This article discusses the role of the randomized controlled trial (RCT) in plastic surgery. There are unique challenges in the execution of an RCT in plastic surgery, including: (1) surgical equipoise, (2) the surgical learning curve, (3) differential care, (4) randomization, (5) concealment, (6) expertise-based design, (7) blinding, (8) intention-to-treat analysis, (9) loss to follow-up, and (10) treatment effect and implications for sample …

Authors

Thoma A; Sprague S; Temple C; Archibald S

Journal

Clinics in Plastic Surgery, Vol. 35, No. 2, pp. 275–284

Publisher

Elsevier

Publication Date

April 2008

DOI

10.1016/j.cps.2007.10.011

ISSN

0094-1298