Does the location of thrombosis determine the risk of disease recurrence in patients with proximal deep vein thrombosis?∗∗Access the “Journal Club” discussion of this paper at http://www.elsevier.com/locate/ajmselect/

PURPOSE: To determine if the location of deep vein thrombosis is a predictor of recurrent venous thromboembolism during the initial 3 months of anticoagulant therapy. METHODS: The study population consisted of 1,149 consecutive patients with symptomatic proximal deep vein thrombosis. In all patients, deep vein thrombosis was confirmed by Duplex ultrasound or venography and was classified as popliteal, femoral, or iliofemoral. Patients received …