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Warfarin Interactions With Antibiotics in the...
Journal article

Warfarin Interactions With Antibiotics in the Ambulatory Care Setting

Abstract

IMPORTANCE: The effect of antibiotic coadministration on the international normalized ratio (INR) in a relatively stable, real-world warfarin population has not been adequately described. Case reports and studies of healthy volunteers do not account for the potential contribution of acute illness to INR variability. OBJECTIVE: To compare the risk of excessive anticoagulation among patients with stable warfarin therapy purchasing an antibiotic …

Authors

Clark NP; Delate T; Riggs CS; Witt DM; Hylek EM; Garcia DA; Ageno W; Dentali F; Crowther MA

Journal

JAMA Internal Medicine, Vol. 174, No. 3, pp. 409–416

Publisher

American Medical Association (AMA)

Publication Date

March 1, 2014

DOI

10.1001/jamainternmed.2013.13957

ISSN

2168-6106