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Male/Female Differences in Indomethacin Effects in...

Journal article

Male/Female Differences in Indomethacin Effects in Preterm Infants

Abstract

To test whether indomethacin prophylaxis has sex-mediated effects on severe intraventricular hemorrhage (grade III and IV) and on long-term outcomes in extremely-low-birth-weight infants. A secondary analysis was performed in the entire "Trial of Indomethacin Prophylaxis in Preterms study" cohort. The results suggest a weak differential treatment effect of indomethacin by sex.

Authors

Ohlsson A; Roberts RS; Schmidt B; Davis P; Moddeman D; Saigal S; Solimano A; Vincer M; Wright L; Investigators TTOIPIP

Journal

The Journal of Pediatrics, Vol. 147, No. 6, pp. 860–862

Publisher

Elsevier

Publication Date

December 1, 2005

DOI

10.1016/j.jpeds.2005.07.032

ISSN

0022-3476

Associated Experts

Robin Sydney Roberts

Professor Emeritus, Faculty of Health Sciences

Saroj Saigal

Professor Emeritus, Faculty of Health Sciences

Labels

Fields of Research (FoR)

3213 Paediatrics 32 Biomedical and Clinical Sciences

Medical Subject Headings (MeSH)

Anti-Inflammatory Agents, Non-Steroidal Cerebral Ventricles Developmental Disabilities Female Humans Indomethacin Infant, Newborn Infant, Premature Infant, Very Low Birth Weight Intracranial Hemorrhages Male Sex Factors Treatment Outcome

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