Journal article
Vagus Nerve Stimulation for Treatment of Partial Seizures: 1. A Controlled Study of Effect on Seizures
Abstract
Vagus nerve stimulation (VNS) was shown to reduce seizure frequency in refractory epilepsy patients in two pilot studies. Based on these results, a multicenter, prospectively randomized, parallel, double-blind study of patients with refractory partial seizures was initiated. After a 12-week baseline period, identical vagus nerve stimulators were implanted and patients randomized to either a high or low 14-week VNS treatment paradigm. The …
Authors
Ben‐Menachem E; Mañon‐Espaillat R; Ristanovic R; Wilder BJ; Stefan H; Mirza W; Tarver WB; Wernicke JF; Group IVNSS
Journal
Epilepsia, Vol. 35, No. 3, pp. 616–626
Publisher
Wiley
Publication Date
May 1994
DOI
10.1111/j.1528-1157.1994.tb02482.x
ISSN
0013-9580
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AdolescentAdultAgedAnticonvulsantsChildCombined Modality TherapyDouble-Blind MethodElectric Stimulation TherapyElectrodes, ImplantedEpilepsies, PartialEquipment DesignFemaleFollow-Up StudiesHumansMagneticsMaleMedical RecordsMiddle AgedProspective StudiesProstheses and ImplantsSeverity of Illness IndexTreatment OutcomeVagus Nerve