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Role of Several Mediators of Inflammation on the...
Journal article

Role of Several Mediators of Inflammation on the Mouse Hypothalamo-Pituitary-Adrenal Axis Response during Acute Endotoxemia

Abstract

Cytokines secreted by bacterial endotoxin-activated immune cells are substances known to stimulate the hypothalamo-pituitary-adrenal (HPA) axis function. The present study was designed to better understand the effect of different mediators of inflammation, such as cytokines and histamine, on the acute HPA axis response induced by administration of a single dose of bacterial lipopolysaccharide (LPS) in adult, male, BALB/c mice. Two different …

Authors

Hadid R; Spinedi E; Chautard T; Giacomini M; Gaillard RC

Journal

NeuroImmunoModulation, Vol. 6, No. 5, pp. 336–343

Publisher

Karger Publishers

Publication Date

1999

DOI

10.1159/000026393

ISSN

1021-7401