Journal article
Reduced expression of hemopoietic cytokine receptors on cord blood progenitor cells in neonates at risk for atopy
Abstract
BACKGROUND: Recent findings point to an association between allergic asthma in adults and increased responsiveness of myeloid progenitor cells to certain hemopoietic growth factors. However, it is not clear at what age these changes in progenitor cells first become manifest, although increasing evidence suggests that the allergic phenotype may begin to emerge in very early life.
OBJECTIVE: We sought to compare expression of hemopoietic cytokine …
Authors
Upham JW; Hayes LM; Lundahl J; Sehmi R; Denburg JA
Journal
The Journal of Allergy and Clinical Immunology, Vol. 104, No. 2, pp. 370–375
Publisher
Elsevier
Publication Date
8 1999
DOI
10.1016/s0091-6749(99)70381-7
ISSN
0091-6749
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AdultAntigens, CD34CD3 ComplexFemaleFetal BloodGenetic Predisposition to DiseaseHematopoietic Stem CellsHumansHypersensitivity, ImmediateInfant, NewbornPregnancyReceptors, CytokineReceptors, Granulocyte-Macrophage Colony-Stimulating FactorReceptors, Growth FactorReceptors, IgGReceptors, InterleukinReceptors, Interleukin-3Receptors, Interleukin-5Risk Factors