Conference
Regulation of IL-5 Receptor on Eosinophil Progenitors in Allergic Inflammation: Role of Retinoic Acid
Abstract
We and others have shown that IL-5 plays a central role in eosinophil and basophil differentiation, exerting its effects through the IL-5 receptor (IL-5R). Little is currently known concerning regulation of IL-5Ralpha gene transcription in the context of commitment of hemopoietic progenitor cells to the eosinophil and basophil lineages; recent studies have indicated that IL-5 itself can regulate IL-5Ralpha expression on mature eosinophils. We …
Authors
Denburg JA; Sehmi R; Upham J
Volume
124
Pagination
pp. 246-248
Publisher
Karger Publishers
Publication Date
2001
DOI
10.1159/000053724
Conference proceedings
International Archives of Allergy and Immunology
Issue
1-3
ISSN
1018-2438