Journal article
Identification of guinea pig eosinophil chemotactic factor of anaphylaxis as leukotriene B4 and 8(S),15(S)-dihydroxy-5,9,11,13(Z,E,Z,E)-eicosatetraenoic acid.
Abstract
We have purified and characterized the guinea pig eosinophil chemotactic factor of anaphylaxis (ECF-A), an activity previously described in diffusates from sensitized lung challenged with specific Ag that appeared to selectively attract eosinophils from mixed leukocyte populations. Time course studies showed that the release of ECF-A from challenged presensitized guinea pig lung fragments closely paralleled the release of immunoreactive …
Authors
Sehmi R; Cromwell O; Taylor GW; Kay AB
Journal
The Journal of Immunology, Vol. 147, No. 7, pp. 2276–2283
Publisher
Oxford University Press (OUP)
Publication Date
October 1, 1991
DOI
10.4049/jimmunol.147.7.2276
ISSN
0022-1767