Journal article
Components of airway hyperresponsiveness and their associations with inflammation and remodeling in mice
Abstract
BACKGROUND: Pathologic changes, including inflammation and remodeling, occur in the asthmatic airway. However, their relative contribution to the components of airway hyperresponsiveness (AHR) remains unclear.
OBJECTIVE: Attempting to delineate AHR into discrete immune-mediated and structural remodeling components, we performed a detailed time course of the development, progression, and persistence of maximal respiratory system resistance, …
Authors
Southam DS; Ellis R; Wattie J; Inman MD
Journal
Journal of Allergy and Clinical Immunology, Vol. 119, No. 4, pp. 848–854
Publisher
Elsevier
Publication Date
April 2007
DOI
10.1016/j.jaci.2006.12.623
ISSN
0091-6749