Journal article
Reduction of Cardiovascular Risk by Regression of Electrocardiographic Markers of Left Ventricular Hypertrophy by the Angiotensin-Converting Enzyme Inhibitor Ramipril
Abstract
BACKGROUND: Electrocardiographic markers of left ventricular hypertrophy (LVH) predict poor prognosis. We determined whether the ACE inhibitor ramipril prevents the development and causes regression of ECG-LVH and whether these changes are associated with improved prognosis independent of blood pressure reduction.
METHODS AND RESULTS: In the Heart Outcomes Prevention Evaluation (HOPE) study, patients at high risk were randomly assigned to …
Authors
Mathew J; Sleight P; Lonn E; Johnstone D; Pogue J; Yi Q; Bosch J; Sussex B; Probstfield J; Yusuf S
Journal
Circulation, Vol. 104, No. 14, pp. 1615–1621
Publisher
Wolters Kluwer
Publication Date
October 2, 2001
DOI
10.1161/hc3901.096700
ISSN
0009-7322