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Properties of a store-operated nonselective cation...
Journal article

Properties of a store-operated nonselective cation channel in airway smooth muscle

Abstract

Passive depletion of internal Ca(2+) stores in airway smooth muscle (ASM) activates nonselective cation channels (NSCCs) that mediate capacitative Ca(2+) entry. However, the single channel properties of these cation channels have yet to be resolved and their regulation by cytosolic Ca(2+) levels ([Ca(2+)](i)) still remains unclear. NSCC currents and changes in [Ca(2+)](i) during passive depletion of internal Ca(2+) stores were monitored in …

Authors

Helli PB; Janssen LJ

Journal

European Respiratory Journal, Vol. 32, No. 6, pp. 1529–1538

Publisher

European Respiratory Society (ERS)

Publication Date

12 2008

DOI

10.1183/09031936.00054608

ISSN

0903-1936