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Local Antibiotics and the Risk of Antimicrobial...
Journal article

Local Antibiotics and the Risk of Antimicrobial Resistance in Extremity Fractures Complicated by Fracture-Related Infection

Abstract

BACKGROUND: We evaluated antimicrobial resistance (AMR) patterns following local antibiotic use in a large cohort of patients with fractures from the PREP-IT (A Program of Randomized Trials to Evaluate Preoperative Antiseptic Skin Solutions in Orthopaedic Trauma) study. We hypothesized that, among patients with extremity fractures who developed fracture-related infection (FRI), there would be no difference in AMR rates between those who had or …

Authors

Schrank GM; Jozefowski N; Zura RD; Jeray KJ; Gary JL; Gaski GE; Shannon SF; Bzovsky S; Sprague S; Slobogean GP

Journal

Journal of Bone and Joint Surgery-American Volume, Vol. 107, No. Suppl 1, pp. 28–35

Publisher

Wolters Kluwer

Publication Date

June 18, 2025

DOI

10.2106/jbjs.24.01178

ISSN

0021-9355