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Differentiating upper- and lower motor neuron...
Journal article

Differentiating upper- and lower motor neuron diseases using automated acoustic analysis

Abstract

OBJECTIVE: Motor neuron diseases (MNDs) result in a spectrum of motor impairments, including considerable effects on speech function, which manifest as dysarthria-a motor speech disorder. Speech metrics are increasingly recognized as critical biomarkers with potential utility in disease diagnosis and phenotyping. This study aimed to (1) characterize acoustics of upper motor neuron (UMN) and lower motor neuron (LMN) dysarthria presentations in …

Authors

Truong J; Simmatis L; Pommée T; Abrahao A; Adams K; Chum M; O’Connell C; Genge A; Kalra S; Ritsma B

Journal

Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, Vol. 26, No. 7-8, pp. 691–701

Publisher

Taylor & Francis

Publication Date

October 2, 2025

DOI

10.1080/21678421.2025.2506444

ISSN

2167-8421