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A130 EVALUATING PLACEBO RATES IN EOSINOPHILIC...
Journal article

A130 EVALUATING PLACEBO RATES IN EOSINOPHILIC ESOPHAGITIS RANDOMIZED CONTROLLED TRIALS: A SYSTEMATIC REVIEW AND META-ANALYSIS

Abstract

AbstractBackground

Eosinophilic esophagitis (EoE) is a chronic inflammatory and progressive fibrotic condition of the esophagus. There are limited treatment options for EoE and a substantial unmet need for effective and safe medical therapies. Drug development in EoE has been hampered by heterogeneous placebo response rates and uncertainty regarding appropriate endpoint configurations. Accurate characterization of placebo response in EoE …

Authors

Ahmed NS; Rivas A; Yuan Y; Qasim A; O’Gorman D; Feagan B; Jairath V; Bredenoord A; Dellon ES; Ma C

Journal

Journal of the Canadian Association of Gastroenterology, Vol. 8, No. Supplement_1, pp. i51–i52

Publisher

Oxford University Press (OUP)

Publication Date

February 10, 2025

DOI

10.1093/jcag/gwae059.130

ISSN

2515-2084