Xylazine: An Emerging Threat in Obstetrics

Xylazine, an alpha-adrenergic agent, is a common adulterant in the non-prescribed opioid supply. It has multiplicative sedative effects when used with opioids and these effects can negatively impact pregnancy. Given that the opioid epidemic in Canada is not abating and continues to evolve, cases of xylazine exposure during pregnancy are beginning to present in obstetrical units and emergency departments. Rapid dissemination regarding the obstetrical and medical complications that may be seen in patients presenting with unstable opioid use disorders is needed.