Serological Characterisation of a Mouse Monoclonal...

Serological Characterisation of a Mouse Monoclonal Anti‐P‐Like Antibody

Abstract

An IgM mouse monoclonal antibody, LM 147/328, raised against an Escherichia coli immunogen, was found to possess anti-P-like specificity. It is proposed that this antibody recognises an epitope on a Gal beta 1-3GalNAc disaccharide structure (GalNAc = N-acetyl-D-galactosamine). The haemagglutinating activity of this antibody was consistently strong with adult erythrocytes, but gave significantly weak reactions with about 7% of cord erythrocyte samples.

Authors

Inglis G; Fraser RH; Mitchell AAB; Mackie A; Allan EK; Mitchell R

Journal

Vox Sanguinis, Vol. 52, No. 1‐2, pp. 79–82

Publisher

Wiley

Publication Date

March 1, 1987

DOI

10.1111/j.1423-0410.1987.tb02995.x

ISSN

0042-9007

Associated Experts

Gabrielle Inglis

Assistant Professor, Faculty of Health Sciences

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