Journal article
Effectiveness of Ustekinumab for Patients With Moderate-to-Severe Ulcerative Colitis: A Multicenter Real-World Canadian Study
Abstract
INTRODUCTION: We aimed to evaluate the real-world effectiveness and safety of ustekinumab for the treatment of both bio-naive and bio-exposed ulcerative colitis patients in a real-world setting.
METHODS: Retrospective, Canadian multicenter cohort study. Primary outcomes were clinical remission and endoscopic remission. Key secondary outcomes included composite clinical and endoscopic response, safety, and persistence. Univariable logistic …
Authors
Solitano V; Narula N; Ma C; Nanayakkara A; Suarez KE; Zoughlami A; Guizzetti L; Bessissow T; Jairath V
Journal
The American Journal of Gastroenterology, Vol. 120, No. 7, pp. 1576–1584
Publisher
Wolters Kluwer
Publication Date
July 2025
DOI
10.14309/ajg.0000000000003212
ISSN
0002-9270