In vivo mapping of the intra-cortical vasculature and layer-specific changes in Δχ and ΔR2* of human cerebral cortex using USPIO-MRI at 7T

Motivation: In vivo imaging of intra-cortical vessels of human brain, including penetrating arteries, veins and capillary density are still scarce. Goal(s): To reconstruct the in vivo intra-cortical vessels of the human brain and estimate the cortical layer-specific changes in susceptibility (χ) in the presence of superparamagnetic iron oxides. Approach: With aid of Ferumoxytol at 7T, high resolution gradient echo imaging was implemented to …