Journal article
Slowly Inactivating Potassium Conductance (ID)
Abstract
BACKGROUND AND PURPOSE: Excessive accumulation of extracellular glutamate results in the death of most, but not all, neurons in the central nervous system. Understanding the unique properties of cells that can withstand this excitotoxic challenge may identify specific targets for novel stroke therapies.
METHODS: A combination of in vivo methods for analysis of excitotoxic cell death after activation of N-methyl-D-aspartate (NMDA) receptors and …
Authors
Bains JS; Follwell MJ; Latchford KJ; Anderson JW; Ferguson AV
Journal
Stroke, Vol. 32, No. 11, pp. 2624–2634
Publisher
Wolters Kluwer
Publication Date
November 1, 2001
DOI
10.1161/hs1101.098332
ISSN
0039-2499
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
4-AminopyridineAngiotensin IIAngiotensin Receptor AntagonistsAnimalsCell DeathCells, CulturedElectric ConductivityExcitatory Postsynaptic PotentialsHumansHypothalamusKineticsMaleN-MethylaspartateNeuronsNeuroprotective AgentsParaventricular Hypothalamic NucleusPatch-Clamp TechniquesPotassium Channel BlockersPotassium ChannelsRatsRats, Inbred SHRRats, Sprague-DawleyStroke