Journal article
Abstract P448: Follistatin Improves Vascular Function by Regulating Perivascular Adipose Tissue in Essential Hypertension
Abstract
Introduction: Essential hypertension is characterized by resistance artery remodeling induced by oxidative stress. Most vessels are surrounded by perivascular adipose tissue (PVAT) which regulates vascular tone via release of vasoactive substances. In physiological conditions, PVAT induces an anticontractile effect. In pathological conditions such as hypertension, PVAT exhibit increased oxidative stress resulting in augmented contraction and …
Authors
Kuganathan A; Lu V; Gao B; MacDonald M; Dickhout J; Krepinsky J
Journal
Hypertension, Vol. 81, No. Suppl_1, pp. ap448–ap448
Publisher
Wolters Kluwer
Publication Date
September 2024
DOI
10.1161/hyp.81.suppl_1.p448
ISSN
0194-911X