Septal Lesions and Resting Adrenal Function. A Possible Explanation of Conflicting Findings

Plasma corticosterone values were obtained using cortico-sterone-binding-globulin florisil assay for normal, sham-lesioned and septal-lesioned rats at 2 time periods, 12 h apart, corresponding to 2 h after the switch to light or dark under a 12:12 h light:dark regime. At a time 2 h after the switch to light, when normal and sham-lesioned animals evidenced low resting corticosterone responses, septal rats exhibited a fivefold increase in resting …