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Postoperative pain and neurocognitive outcomes...
Journal article

Postoperative pain and neurocognitive outcomes after noncardiac surgery: a systematic review and dose–response meta-analysis

Abstract

BACKGROUND: Postoperative delirium (POD) and postoperative cognitive dysfunction (POCD) are common after noncardiac surgery. Postsurgical pain is frequent and can persist as chronic postsurgical pain (CPSP). The association between postsurgical pain and POD or POCD is biologically plausible. We conducted this systematic review to evaluate the association between acute postsurgical pain or CPSP and POD or POCD in adults undergoing noncardiac …

Authors

Khaled M; Sabac D; Fuda M; Koubaesh C; Gallab J; Qu M; Lo Bianco G; Shanthanna H; Paul J; Thabane L

Journal

British Journal of Anaesthesia, Vol. 134, No. 1, pp. 89–101

Publisher

Elsevier

Publication Date

1 2025

DOI

10.1016/j.bja.2024.08.032

ISSN

0007-0912