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Methotrexate and Tumor Necrosis Factor Inhibitors...
Journal article

Methotrexate and Tumor Necrosis Factor Inhibitors Independently Decrease Neutralizing Antibodies after SARS-CoV-2 Vaccination: Updated Results from the SUCCEED Study

Abstract

Objective: SARS-CoV-2 remains the third most common cause of death in North America. We studied the effects of methotrexate and tumor necrosis factor inhibitor (TNFi) on neutralization responses after COVID-19 vaccination in immune-mediated inflammatory disease (IMID). Methods: Prospective data and sera of adults with inflammatory bowel disease (IBD), rheumatoid arthritis (RA), spondyloarthritis (SpA), psoriatic arthritis (PsA), and systemic …

Authors

Hitchon CA; Bowdish DME; Boire G; Fortin PR; Flamand L; Chandran V; Dayam RM; Gingras A-C; Card CM; Colmegna I

Journal

Vaccines, Vol. 12, No. 9,

Publisher

MDPI

DOI

10.3390/vaccines12091061

ISSN

2076-393X