Journal article
Mutation in the S gene of hepatitis B virus and anti‐HBs subtype‐nonspecificity contributed to the co‐existence of HBsAg and anti‐HBs in patients with chronic hepatitis B virus infection
Abstract
The mechanism for the co-existence of hepatitis B surface antigen (HBsAg) and antibodies to HBsAg (anti-HBs) in chronic HBV infected patients remains controversial. This study aimed to explore the role of HBV S gene mutation and anti-HBs subtype-nonspecificity in patients with simultaneous HBsAg/anti-HBs positivity. Chronic HBV infections with (n = 145, group I) and without (n = 141, group II) anti-HBs were included. The S gene was amplified …
Authors
Fu X; Chen J; Chen H; Lin J; Xun Z; Li S; Liu C; Zeng Y; Chen T; Yang B
Journal
Journal of Medical Virology, Vol. 89, No. 8, pp. 1419–1426
Publisher
Wiley
Publication Date
August 2017
DOI
10.1002/jmv.24782
ISSN
0146-6615