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Evolution of substrate specificity in bacterial...
Journal article

Evolution of substrate specificity in bacterial AA10 lytic polysaccharide monooxygenases

Abstract

BackgroundUnderstanding the diversity of lignocellulose-degrading enzymes in nature will provide insights for the improvement of cellulolytic enzyme cocktails used in the biofuels industry. Two families of enzymes, fungal AA9 and bacterial AA10, have recently been characterized as crystalline cellulose or chitin-cleaving lytic polysaccharide monooxygenases (LPMOs). Here we analyze the sequences, structures, and evolution of LPMOs to understand …

Authors

Book AJ; Yennamalli RM; Takasuka TE; Currie CR; Phillips GN; Fox BG

Journal

Biotechnology for Biofuels and Bioproducts, Vol. 7, No. 1,

Publisher

Springer Nature

Publication Date

December 2014

DOI

10.1186/1754-6834-7-109

ISSN

1754-6834