Journal article
Higher Affinity Enables More Accurate Detection of SARS‐CoV‐2 in Human Saliva Using Aptamer‐Based Litmus Test
Abstract
Many aptamers have been generated by systematic evolution of ligands by exponential enrichment (SELEX) to recognize spike proteins of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2&ek), some of which have been engineered into dimeric and trimeric versions for enhanced affinity for diagnostic applications. However, no studies have been conducted to compare the utilities of monomeric, dimeric and trimeric aptamers in diagnostic …
Authors
Liu R; Li J; Gu J; Salena BJ; Li Y
Journal
Angewandte Chemie International Edition, Vol. 63, No. 47,
Publisher
Wiley
Publication Date
November 18, 2024
DOI
10.1002/anie.202407049
ISSN
1433-7851