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A Randomized Trial Comparing Concurrent versus...
Journal article

A Randomized Trial Comparing Concurrent versus Sequential Radiation and Endocrine Therapy in Early-Stage, Hormone-Responsive Breast Cancer

Abstract

Concerns exist regarding increased toxicities, including endocrine therapy toxicity, with concurrent radiation and endocrine therapy in early breast cancer (EBC). We present a pragmatic, randomized trial comparing concurrent versus sequential endocrine and radiotherapy in hormone-responsive EBC. In this multicenter trial, patients were randomized to receive adjuvant endocrine therapy concurrent with, or sequential to, radiotherapy. The primary …

Authors

McGee SF; Clemons M; Pond G; Caudrelier J-M; Liu M; Alzahrani MJ; Ng TL; Awan AA; Sehdev S; Hilton J

Journal

Current Oncology, Vol. 31, No. 8, pp. 4531–4545

Publisher

MDPI

DOI

10.3390/curroncol31080338

ISSN

1198-0052