Voltage-Dependent and Receptor-Operated Calcium Channels

Contraction of airways smooth muscle is universally accepted as being the principal component of the acute phase of airflow limitation that characterizes an asthmatic attack. It is also acknowledged that the airway structure of asthmatic subjects is abnormal. The abnormality is, in all likelihood, a consequence of the profound inflammatory processes that thicken the airway wall and promote transudation of mucus and oedema fluid into the airway …