Journal article
A Phase II Study of 5-Fluorouracil Plus High-Dose Folinic Acid in the Treatment of Recurrent Small Cell Lung Cancer
Abstract
Fourteen patients with small cell lung cancer (SCLC) previously treated with one or two chemotherapy regimens were entered in this study. 5-Fluorouracil 370 mg/m2 or 300 mg/m2 was given with folinic acid 200 mg/m2 by i.v. rapid infusion on days 1 through 5. Cycles were repeated every 28 days. There were no objective responses. One patient had stable disease for 47 weeks. The overall median survival duration was 23 weeks. Toxicity was comparable …
Authors
Stewart DJ; Dahrouge S; Soltys KM; Evans WK
Journal
American Journal of Clinical Oncology, Vol. 18, No. 2, pp. 130–132
Publisher
Wolters Kluwer
Publication Date
April 1995
DOI
10.1097/00000421-199504000-00007
ISSN
0277-3732