Abstract Background Gender-based violence (GBV) disproportionately affects young women and LGBTQ+ individuals, and therefore, a systematic review and meta-analysis was carried out to i) qualitatively identify the prevalence and experience of GBV in virtual work environments and ii) evaluate the current workplace policies, interventions or tools to protect against GBV in the workplace.“ Methods A comprehensive search was undertaken following the PRISMA guidelines after registration with PROSPERO (CRD42023399684). PubMed, OVID, Scopus, Web of Science and CINAHL databases were searched using the keywords “Gender,” “GBV,” “workplace,” and “telework.” Results Of the total 1290 studies identified after removing duplicates, 60 were included. Studies included from the global South and global North cover in-person and online/ hybrid work settings. Most of the studies were cross-sectional (42), followed by mixed-methods (10), qualitative (5) and cohort (3). The study included articles on workers in healthcare (33, 55%), academia (16, 27%), skilled trades (7, 11%), and industry (4, 7%). Discussion Bullying, undermining, and harassment (BUH) are most likely experienced by women, minority groups, and homosexuals. Workplace bullying, sexual and physical harassment, gender-based harassment, physical violence, sexual and gender discrimination, and microaggression are some forms of GBV prevalent in healthcare, academia, industry and skilled trades. Cyberbullying resulted in perceived stress and job dissatisfaction among women employees. Conclusion There must be transparency about how the institution(s) handle reports of GBV and clarity regarding the mechanisms for supporting survivors and holding perpetrators accountable. Organizations must create cyberbullying policies, standards, and processes to guarantee that the complaints are handled in a fair, confidential, and transparent manner.