Journal article
Estimated prophylactic dose required to achieve 3% trough as a function of age and concentrate class in multi‐country severe WAPPS‐Hemo haemophilia patients
Abstract
INTRODUCTION: Web-Accessible Population-Pharmacokinetic Service-Haemophilia (WAPPS-Hemo) data are available to study factor-concentrate usage, defined as the required weekly dose to achieve a 3% trough (WD3T), across standard and extended half-life (SHL/EHL) products.
AIM: To provide baseline usage data including (i) differences across plasma-derived (pdSHL) versus recombinant (rSHL) products, (ii) SHL versus EHL, and (iii) effect of age and …
Authors
Hajducek DM; Chelle P; Iorio A; Iserman E; Edginton AN
Journal
Haemophilia, Vol. 30, No. 4, pp. 925–932
Publisher
Wiley
Publication Date
7 2024
DOI
10.1111/hae.15032
ISSN
1351-8216