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Metabolome-associated psychological comorbidities...
Journal article

Metabolome-associated psychological comorbidities improvement in irritable bowel syndrome patients receiving a probiotic

Abstract

Our recent randomized, placebo-controlled study in Irritable Bowel Syndrome (IBS) patients with diarrhea or alternating bowel habits showed that the probiotic Bifidobacterium longum (BL) NCC3001 improves depression scores and decreases brain emotional reactivity. However, the involved metabolic pathways remain unclear. This analysis aimed to investigate the biochemical pathways underlying the beneficial effects of BL NCC3001 using metabolomic …

Authors

Martin F-P; Cominetti O; Berger B; Combremont S; Marquis J; Xie G; Jia W; Pinto-Sanchez MI; Bercik P; Bergonzelli G

Journal

Gut Microbes, Vol. 16, No. 1,

Publisher

Taylor & Francis

Publication Date

December 31, 2024

DOI

10.1080/19490976.2024.2347715

ISSN

1949-0976