Modelling the mechanistic determinants of antimicrobial resistant Escherichia coli and Pseudomonas aeruginosa within private groundwater systems in the Republic of Ireland

Antimicrobial resistant organisms and genes are now recognised as emerging water contaminants with significant potential adverse human and ecological health impacts. For example, the World Health Organisation have recently estimated that the global human health burden associated with antimicrobial infection will likely outstrip cancer mortalities by the year 2050, with >10 million deaths predicted due to these infections. The presence of …