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Stereotactic Radiation for Ultra-Central Non-Small...
Journal article

Stereotactic Radiation for Ultra-Central Non-Small Cell Lung Cancer: A Safety and Efficacy Trial (SUNSET)

Abstract

PURPOSE: The use of stereotactic body radiation therapy for tumors in close proximity to the central mediastinal structures has been associated with a high risk of toxicity. This study (NCT03306680) aimed to determine the maximally tolerated dose of stereotactic body radiation therapy for ultracentral non-small cell lung carcinoma, using a time-to-event continual reassessment methodology. METHODS AND MATERIALS: Patients with T1-3N0M0 (≤6 cm) …

Authors

Giuliani ME; Filion E; Faria S; Kundapur V; Toni Vu TTT; Lok BH; Raman S; Bahig H; Laba JM; Lang P

Journal

International Journal of Radiation Oncology • Biology • Physics, Vol. 120, No. 3, pp. 669–677

Publisher

Elsevier

Publication Date

November 2024

DOI

10.1016/j.ijrobp.2024.03.050

ISSN

0360-3016