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The effect of comb length on the in vitro and in...
Journal article

The effect of comb length on the in vitro and in vivo properties of self-assembled poly(oligoethylene glycol methacrylate)-based block copolymer nanoparticles

Abstract

Comb copolymer analogues of poly(lactic acid)-polyethylene glycol block copolymers (PLA-b-PEG) offer potential to overcome the inherent chemistry and stability limitations of their linear block copolymer counterparts. Herein, we examine the differences between P(L)LA10K-b-PEG10K and linear-comb copolymer analogues thereof in which the linear PEG block is replaced by poly(oligo(ethylene glycol) methacrylate) (POEGMA) blocks with different side …

Authors

Singh A; Lofts A; Krishnan R; Campea M; Chen L; Wan Y; Hoare T

Journal

Nanoscale Advances, Vol. 6, No. 9, pp. 2487–2498

Publisher

Royal Society of Chemistry (RSC)

Publication Date

April 30, 2024

DOI

10.1039/d3na01156a

ISSN

2516-0230