Preprint
Nasopharyngeal metatranscriptomics reveals host-pathogen signatures of pediatric sinusitis
Abstract
Acute sinusitis (AS) is the fifth leading cause of antibiotic prescriptions in children. Distinguishing bacterial AS from common viral upper respiratory infections in children is crucial to prevent unnecessary antibiotic use but is challenging with current diagnostic methods. Despite its speed and cost, untargeted RNA sequencing of clinical samples from children with suspected AS has the potential to overcome several limitations of other …
Authors
AbuMazen N; Chu V; Hunjan M; Lobb B; Lee S; Kurs-Lasky M; Williams JV; MacDonald W; Johnson M; Hirota JA
DOI
10.1101/2024.03.03.24303663
Preprint server
medRxiv