Journal article
Alterations in chromosome 1q in multiple myeloma randomized clinical trials: a systematic review
Abstract
Extra copies of chromosome 1q21 (+1q: gain = 3 copies, amp >= 4 copies) are associated with worse outcomes in multiple myeloma (MM). This systematic review assesses the current reporting trends of +1q, the efficacy of existing regimens on +1q, and its prognostic implications in MM randomized controlled trials (RCTs). Pubmed, Embase and Cochrane Registry of RCTs were searched from January 2012 to December 2022. Only MM RCTs were included. A …
Authors
Neupane K; Fortuna GG; Dahal R; Schmidt T; Fonseca R; Chakraborty R; Koehn KA; Mohan M; Mian H; Costa LJ
Journal
Blood Cancer Journal, Vol. 14, No. 1,
Publisher
Springer Nature
DOI
10.1038/s41408-024-00985-0
ISSN
2044-5385