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Past meets present: Reviving 80‐year‐old Canadian...
Journal article

Past meets present: Reviving 80‐year‐old Canadian dried serum from World War II and its significance in advancing modern freeze‐dried plasma for prehospital management of haemorrhage

Abstract

During World War II, Charles H. Best utilized Charles R. Drew's plasma isolation and drying technique to lead Canada's initiative to provide dried serum as a means of primary resuscitation for British casualties on the frontlines. Serum was likely utilized over plasma for its volume expansion properties without the risk of clotting during prolonged storage. We reconstituted dried serum from 1943 and discovered intact albumin, as well as …

Authors

Singh K; Peng HT; Moes K; Kretz CA; Beckett A

Journal

British Journal of Haematology, Vol. 204, No. 4, pp. 1515–1522

Publisher

Wiley

Publication Date

April 2024

DOI

10.1111/bjh.19298

ISSN

0007-1048