Journal article
Effect of the ketone beta-hydroxybutyrate on markers of inflammation and immune function in adults with type 2 diabetes
Abstract
Pre-clinical and cell culture evidence supports the role of the ketone beta-hydroxybutyrate (BHB) as an immunomodulatory molecule that may inhibit inflammatory signalling involved in several chronic diseases such as type 2 diabetes (T2D), but studies in humans are lacking. Therefore, we investigated the anti-inflammatory effect of BHB in humans across three clinical trials. To investigate if BHB suppressed pro-inflammatory cytokine secretion, …
Authors
Neudorf H; Islam H; Falkenhain K; Oliveira B; Jackson GS; Moreno-Cabañas A; Madden K; Singer J; Walsh JJ; Little JP
Journal
Clinical & Experimental Immunology, Vol. 216, No. 1, pp. 89–103
Publisher
Oxford University Press (OUP)
Publication Date
March 12, 2024
DOI
10.1093/cei/uxad138
ISSN
0009-9104