Journal article
Design of Hydrated Porphyrin‐Phospholipid Bilayers with Enhanced Magnetic Resonance Contrast
Abstract
Computer simulations are used to design more hydrated bilayers, formed from amine-modified porphyrin-phospholipids (PoPs). Experiments confirm that the new constructs give rise to bilayers with greater water content. When chelated with manganese, amine-modified PoPs provide improved contrast for magnetic resonance and are safely used for imaging in vivo.
Authors
Shao S; Nhu T; Razi A; Chitgupi U; Geng J; Alsop RJ; Dzikovski BG; Rheinstädter MC; Ortega J; Karttunen M
Journal
Small, Vol. 13, No. 1,
Publisher
Wiley
Publication Date
1 2017
DOI
10.1002/smll.201602505
ISSN
1613-6810