Journal article
The Good and the Bad of SHROOM3 in Kidney Development and Disease: A Narrative Review
Abstract
Purpose of review: Multiple large-scale genome-wide association meta-analyses studies have reliably identified an association between genetic variants within the SHROOM3 gene and chronic kidney disease. This association extends to alterations in known markers of kidney disease including baseline estimated glomerular filtration rate, urinary albumin-to-creatinine ratio, and blood urea nitrogen. Yet, an understanding of the molecular mechanisms …
Authors
Paul A; Lawlor A; Cunanan K; Gaheer PS; Kalra A; Napoleone M; Lanktree MB; Bridgewater D
Journal
Canadian Journal of Kidney Health and Disease, Vol. 10, ,
Publisher
SAGE Publications
Publication Date
January 2023
DOI
10.1177/20543581231212038
ISSN
2054-3581