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Proton Therapy Mediates Dose Reductions to Brain...
Journal article

Proton Therapy Mediates Dose Reductions to Brain Structures Associated With Cognition in Children With Medulloblastoma

Abstract

PURPOSE: Emerging evidence suggests proton radiation therapy may offer cognitive sparing advantages over photon radiation therapy, yet dosimetry has not been compared previously. The purpose of this study was to examine dosimetric correlates of cognitive outcomes in children with medulloblastoma treated with proton versus photon radiation therapy. METHODS AND MATERIALS: In this retrospective, bi-institutional study, dosimetric and cognitive …

Authors

Sienna J; Kahalley LS; Mabbott D; Grosshans D; Santiago AT; Paulino ADC; Merchant TE; Manzar GS; Dama H; Hodgson DC

Journal

International Journal of Radiation Oncology • Biology • Physics, Vol. 119, No. 1, pp. 200–207

Publisher

Elsevier

Publication Date

May 2024

DOI

10.1016/j.ijrobp.2023.11.035

ISSN

0360-3016