Autonomic Control of Thermogenic Capacity is Optimized in Deer Mice Native to High or Low Altitudes

The North American deer mouse ( Peromyscus maniculatus ) ranges from below sea level to above 4,300 m elevation. To survive the cold hypoxic conditions at altitude, highland populations must sustain high rates of aerobic thermogenesis in an oxygen scarce environment. Here, we investigated whether differences in autonomic control of the cardiovascular system contributes to the increased thermogenic capacity ( V̇ O 2 max) of deer mice native to …