Machine Learning Models Predict PTSD Severity and Functional Impairment: A Personalized Medicine Approach for Uncovering Complex Associations Among Heterogeneous Symptom Profiles

OBJECTIVE: Posttraumatic stress disorder (PTSD) is a debilitating psychiatric illness, experienced by approximately 10% of the population. Heterogeneous presentations that include heightened dissociation, comorbid anxiety and depression, and emotion dysregulation contribute to the severity of PTSD, in turn, creating barriers to recovery. There is an urgent need to use data-driven approaches to better characterize complex psychiatric …